Guide: Application for gene expression analysis

Guide (Genome Informatics Data Explorer) is an application designed for the bench biologists to analyse RNA-Seq and microarray expression data. It performs gene-centric analyses such as differential expression using well-established R modules. It also enables editing of R commands to customise the analyses for advanced users.

Key features include:
• Find differentially expressed genes for an uploaded dataset
• Show multidimensional scaling plot to view sample relationships
• Show expression profile plots of genes
• Customise R functions used for advanced users

You can see some of these features on the screenshots page. Download page has the current version.

Citing Guide

J Choi: Guide: a desktop application for analysing gene expression data. BMC Genomics 2013, 14:688 doi:10.1186/1471-2164-14-688

(Manuscript available at BMC Genomics)

Note that substantial changes have been made to Guide in a recent version, and hence it now works differently in some ways to the description in the paper. More details can be found on the download page.

This is work done as a part of research at the Hilton Lab, at the Walter+Eliza Hall Institute for Medical Research in Melbourne.